Catalog Number - 62508-05P

Hyper Similars C8™ Octyl is a traditional reversed-phase HPLC stationary phase manufactured on high-purity Type-B spherical silica with a fully endcapped octyl (C8) bonded phase. Designed as a cost-effective alternative to legacy Hypersil® and Spherisorb® columns, it offers comparable chromatographic behavior for USP L7 methods while providing the moderate hydrophobic retention and reproducibility expected from a conventional C8 stationary phase. Compared to C18 columns, C8 phases generally provide reduced retention and faster elution of hydrophobic analytes.

62508-05P is a 50 mm x 4.6 mm ID analytical column packed with 5 µm, 150Å Hyper Similars C8 particles. The short 50 mm length is optimized for rapid analyses, reduced solvent consumption, and high-throughput workflows. The 5 µm particle size provides reliable performance with lower operating pressure than smaller particle alternatives, making it well suited for routine use on conventional HPLC systems. Typical operating flow rates are approximately 1.0–2.0 mL/min.

This USP L7 column is ideal for hydrophobic and neutral compounds when less retention is desired than a comparable C18 phase. Common applications include pharmaceutical analysis, long-chain fatty acid separations, quality control testing, and fast analytical methods requiring traditional C8 selectivity.

Key Benefits

• Type-B spherical silica stationary phase

• Suitable alternative for USP L7 methods

• Comparable selectivity to Hypersil® and Spherisorb® C8 columns

• Fast analysis with 50 mm column length

• Lower retention than C18 columns

• Reliable performance with 5 µm particles

• Excellent for hydrophobic and neutral compounds

• End-capped C8 bonded phase

Typical Applications

• USP L7 methods

• Reversed-phase HPLC

• Pharmaceutical analysis

• Quality control testing

• Method development

• Long-chain fatty acid analysis

• Fast analytical separations

• Method transfer and validation

Specifications

• Product Type: HPLC Column

• Stationary Phase: Hyper Similars C8 Octyl

• USP Classification: L7

• Particle Size: 5 µm

• Particle Type: Type-B Spherical Silica

• Bonded Phase: C8 (Octyl)

• Endcapped: Yes

• Pore Size: 150Å

• Column Dimensions: 4.6 mm ID x 50 mm

• Length: 50 mm

• Recommended Flow Rate: 1.0–2.0 mL/min

• Brand: Cogent

Important Notes

• Designed for reversed-phase chromatography

• Short column length provides rapid analyses

• Lower operating pressure than smaller particle columns

• Compatible with conventional HPLC systems

• Provides less retention than comparable C18 stationary phases

• Excellent alternative for many USP L7 methods

• Ideal for high-throughput workflows

  ---